Benzo-fused lactams from a diversity-oriented synthesis (DOS) library as inhibitors of scavenger receptor BI (SR-BI)-mediated lipid uptake

We report a new series of 8-membered benzo-fused lactams that inhibit cellular lipid uptake from HDL particles mediated by Scavenger Receptor, Class B, Type I (SR-BI). The series was identified via a high-throughput screen of the National Institutes of Health Molecular Libraries Small Molecule Repos...

全面介紹

Na minha lista:
書目詳細資料
發表在:Bioorg Med Chem Lett
Main Authors: Dockendorff, Chris, Faloon, Patrick W., Pu, Jun, Yu, Miao, Johnston, Stephen, Bennion, Melissa, Penman, Marsha, Nieland, Thomas J. F., Dandapani, Sivaraman, Perez, José R., Munoz, Benito, Palmer, Michelle A., Schreiber, Stuart L., Krieger, Monty
格式: Artigo
語言:Inglês
出版: 2015
主題:
Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469080/
https://ncbi.nlm.nih.gov/pubmed/25900219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2015.03.073
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍