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Phase I Study of Pasireotide (SOM 230) and Everolimus (RAD001) in Advanced Neuroendocrine Tumors

Octreotide and everolimus have demonstrated efficacy in neuroendocrine tumors. Pasireotide is a somatostatin analog with binding affinity to a broader range of somatostatin receptor subtypes than octreotide. We performed a phase I study to evaluate the safety and feasibility of combining pasireotide...

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Detalhes bibliográficos
Publicado no:Endocr Relat Cancer
Main Authors: Chan, Jennifer A., Ryan, David P., Zhu, Andrew X., Abrams, Thomas A, Wolpin, Brian M, Malinowski, Paige, Regan, Eileen M, Fuchs, Charles S., Kulke, Matthew H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469068/
https://ncbi.nlm.nih.gov/pubmed/22736724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-11-0382
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