A novel bispecific immunotoxin delivered by human bone marrow-derived mesenchymal stem cells to target blood vessels and vasculogenic mimicry of malignant gliomas

BACKGROUND: In previous years, immunotoxins have been shown to be a greatly promising therapeutic tool for brain malignancies, such as gliomas. Human mesenchymal stem cells (hMSCs) exhibit tropism to tumor tissue. However, the effect of bispecific immunotoxins in malignant gliomas is still unknown....

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Vydáno v:Drug Des Devel Ther
Hlavní autoři: Zhang, Yonghong, Sun, Xinlin, Huang, Min, Ke, Yiquan, Wang, Jihui, Liu, Xiao
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2015
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468939/
https://ncbi.nlm.nih.gov/pubmed/26089644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S79475
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