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A novel bispecific immunotoxin delivered by human bone marrow-derived mesenchymal stem cells to target blood vessels and vasculogenic mimicry of malignant gliomas

BACKGROUND: In previous years, immunotoxins have been shown to be a greatly promising therapeutic tool for brain malignancies, such as gliomas. Human mesenchymal stem cells (hMSCs) exhibit tropism to tumor tissue. However, the effect of bispecific immunotoxins in malignant gliomas is still unknown....

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Zhang, Yonghong, Sun, Xinlin, Huang, Min, Ke, Yiquan, Wang, Jihui, Liu, Xiao
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468939/
https://ncbi.nlm.nih.gov/pubmed/26089644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S79475
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