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Histone Deacetylase Inhibitor Romidepsin Inhibits De Novo HIV-1 Infections
Adjunct therapy with the histone deacetylase inhibitor (HDACi) romidepsin increases plasma viremia in HIV patients on combination antiretroviral therapy (cART). However, a potential concern is that reversing HIV latency with an HDACi may reactivate the virus in anatomical compartments with suboptima...
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| Veröffentlicht in: | Antimicrob Agents Chemother |
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| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4468708/ https://ncbi.nlm.nih.gov/pubmed/25896701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00574-15 |
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