N-Acetyltransferase Genotypes and the Pharmacokinetics and Tolerability of para-Aminosalicylic Acid in Patients with Drug-Resistant Pulmonary Tuberculosis

The aim of this study was to examine the relationships between N-acetyltransferase genotypes, pharmacokinetics, and tolerability of granular slow-release para-aminosalicylic acid (GSR-PAS) in tuberculosis patients. The study was a randomized, two-period, open-label, crossover design wherein each pat...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Sy, Sherwin K. B., de Kock, Lizanne, Diacon, Andreas H., Werely, Cedric J., Xia, Huiming, Rosenkranz, Bernd, van der Merwe, Lize, Donald, Peter R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Clinical Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468703/
https://ncbi.nlm.nih.gov/pubmed/25963985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04049-14
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