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Time Trends in Sputum Mycobacterial Load and Two-Day Bactericidal Activity of Isoniazid-Containing Antituberculosis Therapies

Recent early bactericidal activity (EBA) studies of isoniazid-based antituberculosis therapies have shown a lower EBA over the first two treatment days than in earlier years. To quantify this trend and evaluate factors contributing to it, we extracted individual data from 18 studies with a total of...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: De Jager, Veronique, van der Merwe, Lize, Venter, Amour, Donald, Peter R., Diacon, Andreas H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5365658/
https://ncbi.nlm.nih.gov/pubmed/28137798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02088-16
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