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Attenuated Mutants of Ehrlichia chaffeensis Induce Protection against Wild-Type Infection Challenge in the Reservoir Host and in an Incidental Host

Ehrlichia chaffeensis, a tick-borne rickettsial organism, causes the disease human monocytic ehrlichiosis. The pathogen also causes disease in several other vertebrates, including dogs and deer. In this study, we assessed two clonally purified E. chaffeensis mutants with insertions within the genes...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Nair, Arathy D. S., Cheng, Chuanmin, Jaworski, Deborah C., Ganta, Suhasini, Sanderson, Michael W., Ganta, Roman R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468539/
https://ncbi.nlm.nih.gov/pubmed/25916990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00487-15
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