Attenuated Mutants of Ehrlichia chaffeensis Induce Protection against Wild-Type Infection Challenge in the Reservoir Host and in an Incidental Host

Ehrlichia chaffeensis, a tick-borne rickettsial organism, causes the disease human monocytic ehrlichiosis. The pathogen also causes disease in several other vertebrates, including dogs and deer. In this study, we assessed two clonally purified E. chaffeensis mutants with insertions within the genes...

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Vydáno v:Infect Immun
Hlavní autoři: Nair, Arathy D. S., Cheng, Chuanmin, Jaworski, Deborah C., Ganta, Suhasini, Sanderson, Michael W., Ganta, Roman R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
Microbial Immunity and Vaccines
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468539/
https://ncbi.nlm.nih.gov/pubmed/25916990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00487-15
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