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Targeted and Random Mutagenesis of Ehrlichia chaffeensis for the Identification of Genes Required for In vivo Infection

Ehrlichia chaffeensis is a tick transmitted pathogen responsible for the disease human monocytic ehrlichiosis. Research to elucidate gene function in rickettsial pathogens is limited by the lack of genetic manipulation methods. Mutational analysis was performed, targeting to specific and random inse...

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Bibliografiske detaljer
Main Authors: Cheng, Chuanmin, Nair, Arathy D. S., Indukuri, Vijaya V., Gong, Shanzhong, Felsheim, Roderick F., Jaworski, Deborah, Munderloh, Ulrike G., Ganta, Roman R.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3573109/
https://ncbi.nlm.nih.gov/pubmed/23459099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003171
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