Targeted and Random Mutagenesis of Ehrlichia chaffeensis for the Identification of Genes Required for In vivo Infection

Ehrlichia chaffeensis is a tick transmitted pathogen responsible for the disease human monocytic ehrlichiosis. Research to elucidate gene function in rickettsial pathogens is limited by the lack of genetic manipulation methods. Mutational analysis was performed, targeting to specific and random inse...

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Detalhes bibliográficos
Main Authors: Cheng, Chuanmin, Nair, Arathy D. S., Indukuri, Vijaya V., Gong, Shanzhong, Felsheim, Roderick F., Jaworski, Deborah, Munderloh, Ulrike G., Ganta, Roman R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3573109/
https://ncbi.nlm.nih.gov/pubmed/23459099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003171
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