Targeted and Random Mutagenesis of Ehrlichia chaffeensis for the Identification of Genes Required for In vivo Infection

Ehrlichia chaffeensis is a tick transmitted pathogen responsible for the disease human monocytic ehrlichiosis. Research to elucidate gene function in rickettsial pathogens is limited by the lack of genetic manipulation methods. Mutational analysis was performed, targeting to specific and random inse...

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Bibliographic Details
Main Authors: Cheng, Chuanmin, Nair, Arathy D. S., Indukuri, Vijaya V., Gong, Shanzhong, Felsheim, Roderick F., Jaworski, Deborah, Munderloh, Ulrike G., Ganta, Roman R.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3573109/
https://ncbi.nlm.nih.gov/pubmed/23459099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003171
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