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Murine Gammaherpesvirus 68 Pathogenesis Is Independent of Caspase-1 and Caspase-11 in Mice and Impairs Interleukin-1β Production upon Extrinsic Stimulation in Culture

Gammaherpesviruses establish lifelong infections that are associated with the development of cancer. These viruses subvert many aspects of the innate and adaptive immune response of the host. The inflammasome, a macromolecular protein complex that controls inflammatory responses to intracellular dan...

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Publicat a:J Virol
Autors principals: Cieniewicz, Brandon, Dong, Qiwen, Li, Gang, Forrest, James C., Mounce, Bryan C., Tarakanova, Vera L., van der Velden, Adrianus, Krug, Laurie T.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468508/
https://ncbi.nlm.nih.gov/pubmed/25855746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00658-15
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