Murine Gammaherpesvirus 68 Pathogenesis Is Independent of Caspase-1 and Caspase-11 in Mice and Impairs Interleukin-1β Production upon Extrinsic Stimulation in Culture

Gammaherpesviruses establish lifelong infections that are associated with the development of cancer. These viruses subvert many aspects of the innate and adaptive immune response of the host. The inflammasome, a macromolecular protein complex that controls inflammatory responses to intracellular dan...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Cieniewicz, Brandon, Dong, Qiwen, Li, Gang, Forrest, James C., Mounce, Bryan C., Tarakanova, Vera L., van der Velden, Adrianus, Krug, Laurie T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468508/
https://ncbi.nlm.nih.gov/pubmed/25855746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00658-15
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