HIV Blocks Interferon Induction in Human Dendritic Cells and Macrophages by Dysregulation of TBK1

Dendritic cells (DCs) and macrophages are present in the tissues of the anogenital tract, where HIV-1 transmission occurs in almost all cases. These cells are both target cells for HIV-1 and represent the first opportunity for the virus to interfere with innate recognition. Previously we have shown...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Harman, Andrew N., Nasr, Najla, Feetham, Alexandra, Galoyan, Ani, Alshehri, Abdullateef A., Rambukwelle, Dharshini, Botting, Rachel A., Hiener, Bonnie M., Diefenbach, Eve, Diefenbach, Russell J., Kim, Min, Mansell, Ashley, Cunningham, Anthony L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468486/
https://ncbi.nlm.nih.gov/pubmed/25855743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00889-15
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