Particle-to-PFU Ratio of Ebola Virus Influences Disease Course and Survival in Cynomolgus Macaques

This study addresses the role of Ebola virus (EBOV) specific infectivity in virulence. Filoviruses are highly lethal, enveloped, single-stranded negative-sense RNA viruses that can cause hemorrhagic fever. No approved vaccines or therapies exist for filovirus infections, and infectious virus must be...

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發表在:J Virol
Main Authors: Alfson, Kendra J., Avena, Laura E., Beadles, Michael W., Staples, Hilary, Nunneley, Jerritt W., Ticer, Anysha, Dick, Edward J., Owston, Michael A., Reed, Christopher, Patterson, Jean L., Carrion, Ricardo, Griffiths, Anthony
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2015
主題:
Pathogenesis and Immunity
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468478/
https://ncbi.nlm.nih.gov/pubmed/25903348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00649-15
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