Particle-to-PFU Ratio of Ebola Virus Influences Disease Course and Survival in Cynomolgus Macaques

This study addresses the role of Ebola virus (EBOV) specific infectivity in virulence. Filoviruses are highly lethal, enveloped, single-stranded negative-sense RNA viruses that can cause hemorrhagic fever. No approved vaccines or therapies exist for filovirus infections, and infectious virus must be...

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Bibliografische gegevens
Gepubliceerd in:J Virol
Hoofdauteurs: Alfson, Kendra J., Avena, Laura E., Beadles, Michael W., Staples, Hilary, Nunneley, Jerritt W., Ticer, Anysha, Dick, Edward J., Owston, Michael A., Reed, Christopher, Patterson, Jean L., Carrion, Ricardo, Griffiths, Anthony
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2015
Onderwerpen:
Pathogenesis and Immunity
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468478/
https://ncbi.nlm.nih.gov/pubmed/25903348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00649-15
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