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Chimeric MicroRNA-1291 Biosynthesized Efficiently in Escherichia coli Is Effective to Reduce Target Gene Expression in Human Carcinoma Cells and Improve Chemosensitivity

In contrast to the growing interests in studying noncoding RNAs (ncRNAs) such as microRNA (miRNA or miR) pharmacoepigenetics, there is a lack of efficient means to cost effectively produce large quantities of natural miRNA agents. Our recent efforts led to a successful production of chimeric pre-miR...

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Bibliografski detalji
Izdano u:Drug Metab Dispos
Glavni autori: Li, Mei-Mei, Addepalli, Balasubrahmanyam, Tu, Mei-Juan, Chen, Qiu-Xia, Wang, Wei-Peng, Limbach, Patrick A., LaSalle, Janine M., Zeng, Su, Huang, Min, Yu, Ai-Ming
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Pharmacology and Experimental Therapeutics 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468437/
https://ncbi.nlm.nih.gov/pubmed/25934574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.115.064493
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