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Syntheses and Antibacterial Activity of N-Acylated Ciprofloxacin Derivatives Based on the Trimethyl Lock

[Image: see text] Several N-acyl ciprofloxacin quinone derivatives based on a trimethyl lock structure were synthesized, and their in vitro antibacterial activity against a panel of clinically relevant bacteria was evaluated. A few new analogues displayed enhanced activity against Gram-positive spec...

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Bibliografiske detaljer
Udgivet i:ACS Med Chem Lett
Main Authors: Ji, Cheng, Miller, Patricia A., Miller, Marvin J.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2015
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468398/
https://ncbi.nlm.nih.gov/pubmed/26101578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.5b00146
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