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Can insulin signaling pathways be targeted to transport Aβ out of the brain?

Although the causal role of Amyloid-β (Aβ) in Alzheimer’s disease (AD) is unclear, it is still reasonable to expect that lowering concentrations of Aβ in the brain may decrease the risk of developing the neurocognitive symptoms of the disease. Brain capillary endothelial cells forming the blood-brai...

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Detalhes bibliográficos
Publicado no:Front Aging Neurosci
Main Authors: Vandal, Milene, Bourassa, Philippe, Calon, Frédéric
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468380/
https://ncbi.nlm.nih.gov/pubmed/26136681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2015.00114
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