Brain bioavailability of human intravenous immunoglobulin and its transport through the murine blood–brain barrier

Intravenous immunoglobulin (IVIg) is currently evaluated in clinical trials for the treatment of various disorders of the central nervous system. To assess its capacity to reach central therapeutic targets, the brain bioavailability of IVIg must be determined. We thus quantified the passage of IVIg...

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Hlavní autoři: St-Amour, Isabelle, Paré, Isabelle, Alata, Wael, Coulombe, Katherine, Ringuette-Goulet, Cassandra, Drouin-Ouellet, Janelle, Vandal, Milène, Soulet, Denis, Bazin, Renée, Calon, Frédéric
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2013
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3851908/
https://ncbi.nlm.nih.gov/pubmed/24045402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2013.160
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