Brain bioavailability of human intravenous immunoglobulin and its transport through the murine blood–brain barrier

Intravenous immunoglobulin (IVIg) is currently evaluated in clinical trials for the treatment of various disorders of the central nervous system. To assess its capacity to reach central therapeutic targets, the brain bioavailability of IVIg must be determined. We thus quantified the passage of IVIg...

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Main Authors: St-Amour, Isabelle, Paré, Isabelle, Alata, Wael, Coulombe, Katherine, Ringuette-Goulet, Cassandra, Drouin-Ouellet, Janelle, Vandal, Milène, Soulet, Denis, Bazin, Renée, Calon, Frédéric
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3851908/
https://ncbi.nlm.nih.gov/pubmed/24045402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2013.160
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