Systemic Sclerosis Sera Impair Angiogenic Performance of Dermal Microvascular Endothelial Cells: Therapeutic Implications of Cyclophosphamide

In systemic sclerosis (SSc), dermal capillaries are progressively lost with consequent chronic tissue hypoxia insufficiently compensated by angiogenesis. Clinical studies reported that intravenous cyclophosphamide (CYC) may improve SSc-related peripheral microvascular damage. Recently, we showed tha...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Borghini, Annalisa, Manetti, Mirko, Nacci, Francesca, Bellando-Randone, Silvia, Guiducci, Serena, Matucci-Cerinic, Marco, Ibba-Manneschi, Lidia, Weber, Elisabetta
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468204/
https://ncbi.nlm.nih.gov/pubmed/26076019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130166
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