Systemic Sclerosis Sera Impair Angiogenic Performance of Dermal Microvascular Endothelial Cells: Therapeutic Implications of Cyclophosphamide

In systemic sclerosis (SSc), dermal capillaries are progressively lost with consequent chronic tissue hypoxia insufficiently compensated by angiogenesis. Clinical studies reported that intravenous cyclophosphamide (CYC) may improve SSc-related peripheral microvascular damage. Recently, we showed tha...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Borghini, Annalisa, Manetti, Mirko, Nacci, Francesca, Bellando-Randone, Silvia, Guiducci, Serena, Matucci-Cerinic, Marco, Ibba-Manneschi, Lidia, Weber, Elisabetta
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468204/
https://ncbi.nlm.nih.gov/pubmed/26076019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130166
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