Systemic Sclerosis Sera Impair Angiogenic Performance of Dermal Microvascular Endothelial Cells: Therapeutic Implications of Cyclophosphamide

In systemic sclerosis (SSc), dermal capillaries are progressively lost with consequent chronic tissue hypoxia insufficiently compensated by angiogenesis. Clinical studies reported that intravenous cyclophosphamide (CYC) may improve SSc-related peripheral microvascular damage. Recently, we showed tha...

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Veröffentlicht in:PLoS One
Hauptverfasser: Borghini, Annalisa, Manetti, Mirko, Nacci, Francesca, Bellando-Randone, Silvia, Guiducci, Serena, Matucci-Cerinic, Marco, Ibba-Manneschi, Lidia, Weber, Elisabetta
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468204/
https://ncbi.nlm.nih.gov/pubmed/26076019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130166
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