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Proangiogenic effects of soluble α-Klotho on systemic sclerosis dermal microvascular endothelial cells
BACKGROUND: Systemic sclerosis (SSc) is characterized by endothelial cell (EC) apoptosis, impaired angiogenesis and peripheral microvasculopathy. Soluble α-Klotho (sKl) is a pleiotropic molecule with multiple effects on ECs, including antioxidant and vasculoprotective activities. On the EC surface,...
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| Publicado no: | Arthritis Res Ther |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5301388/ https://ncbi.nlm.nih.gov/pubmed/28183357 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-017-1233-0 |
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