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The landscape and therapeutic relevance of cancer-associated transcript fusions

Transcript fusions as a result of chromosomal rearrangements have been a focus of attention in cancer as they provide attractive therapeutic targets. To identify novel fusion transcripts with the potential to be exploited therapeutically, we analyzed RNA sequencing, DNA copy number and gene mutation...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Oncogene
Hauptverfasser: Yoshihara, Kosuke, Wang, Qianghu, Torres-Garcia, Wandaliz, Zheng, Siyuan, Vegesna, Rahulsimham, Kim, Hoon, Verhaak, Roel GW
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468049/
https://ncbi.nlm.nih.gov/pubmed/25500544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.406
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