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The landscape and therapeutic relevance of cancer-associated transcript fusions

Transcript fusions as a result of chromosomal rearrangements have been a focus of attention in cancer as they provide attractive therapeutic targets. To identify novel fusion transcripts with the potential to be exploited therapeutically, we analyzed RNA sequencing, DNA copy number and gene mutation...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncogene
Main Authors: Yoshihara, Kosuke, Wang, Qianghu, Torres-Garcia, Wandaliz, Zheng, Siyuan, Vegesna, Rahulsimham, Kim, Hoon, Verhaak, Roel GW
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468049/
https://ncbi.nlm.nih.gov/pubmed/25500544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.406
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