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The landscape and therapeutic relevance of cancer-associated transcript fusions

Transcript fusions as a result of chromosomal rearrangements have been a focus of attention in cancer as they provide attractive therapeutic targets. To identify novel fusion transcripts with the potential to be exploited therapeutically, we analyzed RNA sequencing, DNA copy number and gene mutation...

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Detalles Bibliográficos
Publicado en:Oncogene
Main Authors: Yoshihara, Kosuke, Wang, Qianghu, Torres-Garcia, Wandaliz, Zheng, Siyuan, Vegesna, Rahulsimham, Kim, Hoon, Verhaak, Roel GW
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468049/
https://ncbi.nlm.nih.gov/pubmed/25500544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.406
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