Reduced accumulation of platinum drugs is not observed in drug-resistant ovarian cancer cell lines derived from cisplatin-treated patients

The resistance of ovarian cancer towards front-line chemotherapy, usually cisplatin or carboplatin in combination with paclitaxel or docetaxel, remains a major clinical challenge. Resistance to these agents has been largely studied using cell lines selected for resistance to agents in vitro. We exam...

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Vydáno v:J Inorg Biochem
Hlavní autoři: Stukova, Marina, Hall, Matthew D., Tsotsoros, Samantha D., Madigan, James P., Farrell, Nicholas P., Gottesman, Michael M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467998/
https://ncbi.nlm.nih.gov/pubmed/26021697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2015.05.003
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