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A Randomized Controlled Trial on the Effect of Tapentadol and Morphine on Conditioned Pain Modulation in Healthy Volunteers

BACKGROUND: Modulatory descending pathways, originating at supraspinal sites that converge at dorsal horn neurons, influence pain perception in humans. Defects in descending pain control are linked to chronic pain states and its restoration may be a valuable analgesic tool. Conditioned pain modulati...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Martini, Chris, van Velzen, Monique, Drewes, Asbjørn, Aarts, Leon, Dahan, Albert, Niesters, Marieke
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467981/
https://ncbi.nlm.nih.gov/pubmed/26076171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128997
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