A Randomized Controlled Trial on the Effect of Tapentadol and Morphine on Conditioned Pain Modulation in Healthy Volunteers

BACKGROUND: Modulatory descending pathways, originating at supraspinal sites that converge at dorsal horn neurons, influence pain perception in humans. Defects in descending pain control are linked to chronic pain states and its restoration may be a valuable analgesic tool. Conditioned pain modulati...

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Bibliographic Details
Published in:PLoS One
Main Authors: Martini, Chris, van Velzen, Monique, Drewes, Asbjørn, Aarts, Leon, Dahan, Albert, Niesters, Marieke
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467981/
https://ncbi.nlm.nih.gov/pubmed/26076171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128997
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