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Cornea nerve fibre state determines analgesic response to tapentadol in fibromyalgia patients without effective endogenous pain modulation

BACKGROUND: Tapentadol is a centrally acting analgesic with μ‐agonistic activity combined with noradrenaline reuptake inhibition. Its mechanism of action relies on improvement of descending pain inhibition. In the current study, tapentadol's ability to enhance conditioned pain modulation (CPM,...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Eur J Pain
Egile Nagusiak: van de Donk, Tine, van Velzen, Monique, Dahan, Albert, Niesters, Marieke
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6790686/
https://ncbi.nlm.nih.gov/pubmed/31162787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejp.1435
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