Modulation of PICALM Levels Perturbs Cellular Cholesterol Homeostasis

PICALM (Phosphatidyl Inositol Clathrin Assembly Lymphoid Myeloid protein) is a ubiquitously expressed protein that plays a role in clathrin-mediated endocytosis. PICALM also affects the internalization and trafficking of SNAREs and modulates macroautophagy. Chromosomal translocations that result in...

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Publicado en:PLoS One
Autores principales: Mercer, Jacob L., Argus, Joseph P., Crabtree, Donna M., Keenan, Melissa M., Wilks, Moses Q., Chi, Jen-Tsan Ashley, Bensinger, Steven J., Lavau, Catherine P., Wechsler, Daniel S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467867/
https://ncbi.nlm.nih.gov/pubmed/26075887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129776
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