Epoxyeicosatrienoic Acids Regulate Macrophage Polarization and Prevent LPS-Induced Cardiac Dysfunction

Macrophages, owning tremendous phenotypic plasticity and diverse functions, were becoming the target cells in various inflammatory, metabolic and immune diseases. Cytochrome P450 epoxygenase 2J2 (CYP2J2) metabolizes arachidonic acid to form epoxyeicosatrienoic acids (EETs), which possess various ben...

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Pubblicato in:J Cell Physiol
Autori principali: Dai, Meiyan, Wu, Lujin, He, Zuowen, Zhang, Shasha, Chen, Chen, Xu, Xizhen, Wang, Peihua, Gruzdev, Artiom, Zeldin, Darryl C., Wang, Dao Wen
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467528/
https://ncbi.nlm.nih.gov/pubmed/25626689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24939
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