Epoxyeicosatrienoic Acids Regulate Macrophage Polarization and Prevent LPS-Induced Cardiac Dysfunction

Macrophages, owning tremendous phenotypic plasticity and diverse functions, were becoming the target cells in various inflammatory, metabolic and immune diseases. Cytochrome P450 epoxygenase 2J2 (CYP2J2) metabolizes arachidonic acid to form epoxyeicosatrienoic acids (EETs), which possess various ben...

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Vydáno v:J Cell Physiol
Hlavní autoři: Dai, Meiyan, Wu, Lujin, He, Zuowen, Zhang, Shasha, Chen, Chen, Xu, Xizhen, Wang, Peihua, Gruzdev, Artiom, Zeldin, Darryl C., Wang, Dao Wen
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467528/
https://ncbi.nlm.nih.gov/pubmed/25626689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24939
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