Epoxyeicosatrienoic acids protect rat hearts against tumor necrosis factor-α-induced injury

Epoxyeicosatrienoic acids (EET), the primary arachidonic acid metabolites of cytochrome P450 2J (CYP2J) epoxygenases, possess potent vasodilatory, anti-inflammatory, antiapoptotic, and mitogenic effects. To date, little is known about the role of CYP2J2 and EETs in tumor necrosis factor (TNF)-α–indu...

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Detalhes bibliográficos
Main Authors: Zhao, Gang, Wang, Jianing, Xu, Xizhen, Jing, Yanyan, Tu, Ling, Li, Xuguang, Chen, Chen, Cianflone, Katherine, Wang, Peihua, Dackor, Ryan T., Zeldin, Darryl C., Wang, Dao Wen
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276469/
https://ncbi.nlm.nih.gov/pubmed/22223859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M017319
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