HSET overexpression fuels tumor progression via centrosome clustering-independent mechanisms in breast cancer patients

Human breast tumors harbor supernumerary centrosomes in almost 80% of tumor cells. Although amplified centrosomes compromise cell viability via multipolar spindles resulting in death-inducing aneuploidy, cancer cells tend to cluster extra centrosomes during mitosis. As a result cancer cells display...

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Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: Pannu, Vaishali, Rida, Padmashree C.G., Ogden, Angela, Turaga, Ravi Chakra, Donthamsetty, Shashikiran, Bowen, Nathan J., Rudd, Katie, Gupta, Meenakshi V., Reid, Michelle D., Cantuaria, Guilherme, Walczak, Claire E., Aneja, Ritu
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2015
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467423/
https://ncbi.nlm.nih.gov/pubmed/25788277
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