Amplified centrosomes may underlie aggressive disease course in pancreatic ductal adenocarcinoma

Centrosome amplification (CA), the presence of centrosomes that are abnormally numerous or enlarged, is a well-established driver of tumor initiation and progression associated with poor prognosis across a diversity of malignancies. Pancreatic ductal adenocarcinoma (PDAC) carries one of the most dis...

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Publicat a:Cell Cycle
Autors principals: Mittal, Karuna, Ogden, Angela, Reid, Michelle D, Rida, Padmashree CG, Varambally, Sooryanarayana, Aneja, Ritu
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2015
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Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614944/
https://ncbi.nlm.nih.gov/pubmed/26151406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1068478
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