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Die-hard survivors: heterogeneity in apoptotic thresholds may underlie chemoresistance

The unmatched efficacy of microtubule-targeting agents (MTAs) as chemotherapeutics was once assumed to originate from their impact on mitotic processes; however, this misconception is being eroded by amassing data that MTAs instead target interphase functions in patients’ tumors. What remains murky...

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Detalles Bibliográficos
Publicado en:Expert Rev Anticancer Ther
Main Authors: Ogden, Angela, Rida, Padmashree CG, Reid, Michelle D., Kucuk, Omer, Aneja, Ritu
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457617/
https://ncbi.nlm.nih.gov/pubmed/25695344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/14737140.2015.1016425
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