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The pharmacokinetic effect of coadministration of apremilast and methotrexate in individuals with rheumatoid arthritis and psoriatic arthritis

Apremilast is a novel agent for the treatment of inflammatory based autoimmune disorders. The objective of this study was to assess the pharmacokinetic effects of co administration of apremilast and methotrexate on both agents. This was an open-label, multi-center, 3-treatment period, sequential stu...

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Bibliographische Detailangaben
Veröffentlicht in:Clin Pharmacol Drug Dev
Hauptverfasser: Liu, Yong, Zhou, Simon, Nissel, James, Wu, Anfan, Lau, Henry, Palmisano, Maria
Format: Artigo
Sprache:Inglês
Veröffentlicht: BlackWell Publishing Ltd 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467241/
https://ncbi.nlm.nih.gov/pubmed/26097790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.109
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