A novel cancer immunotherapy based on the combination of a synthetic carbohydrate-pulsed dendritic cell vaccine and glycoengineered cancer cells

Immune tolerance to tumor-associated carbohydrate antigens (TACAs) has severely restricted the usefulness of most TACAs. To overcome this problem, we selected a sialylated trisaccharide TACA, GM3, as a target antigen, and tested a new immunotherapeutic strategy by combining metabolic bioengineering...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Qiu, Lei, Li, Jie, Yu, Shichong, Wang, Qianli, Li, Yinghua, Hu, Zhenlin, Wu, Qiuye, Guo, Zhongwu, Zhang, Junping
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467142/
https://ncbi.nlm.nih.gov/pubmed/25760071
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