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p53 activates G(1) checkpoint following DNA damage by doxorubicin during transient mitotic arrest

Recovery from DNA damage is critical for cell survival. The serious damage is not able to be repaired during checkpoint and finally induces cell death to prevent abnormal cell growth. In this study, we demonstrated that 8N-DNA contents are accumulated via re-replication during prolonged recovery per...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: Hyun, Sun-Yi, Jang, Young-Joo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467116/
https://ncbi.nlm.nih.gov/pubmed/25605022
Tagiau: Ychwanegu Tag
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