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Interlocus gene conversion explains at least 2.7 % of single nucleotide variants in human segmental duplications
BACKGROUND: Interlocus gene conversion (IGC) is a recombination-based mechanism that results in the unidirectional transfer of short stretches of sequence between paralogous loci. Although IGC is a well-established mechanism of human disease, the extent to which this mutagenic process has shaped ove...
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| Publicado en: | BMC Genomics |
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| Autor Principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4467073/ https://ncbi.nlm.nih.gov/pubmed/26077037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-1681-3 |
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