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Rapid and accurate large-scale genotyping of duplicated genes and discovery of novel sites of interlocus gene conversion

Over 900 genes have been annotated within duplicated regions of the human genome, yet their functions and potential roles in disease remain largely unknown. One major obstacle has been our inability to accurately and comprehensively assay genetic variation for these genes in a high-throughput manner...

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Detalhes bibliográficos
Main Authors: Nuttle, Xander, Huddleston, John, O'Roak, Brian J., Antonacci, Francesca, Fichera, Marco, Romano, Corrado, Shendure, Jay, Eichler, Evan E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985568/
https://ncbi.nlm.nih.gov/pubmed/23892896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2572
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