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Interlocus gene conversion events introduce deleterious mutations into at least 1% of human genes associated with inherited disease
Establishing the molecular basis of DNA mutations that cause inherited disease is of fundamental importance to understanding the origin, nature, and clinical sequelae of genetic disorders in humans. The majority of disease-associated mutations constitute single-base substitutions and short deletions...
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| Main Authors: | , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Cold Spring Harbor Laboratory Press
2012
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3290778/ https://ncbi.nlm.nih.gov/pubmed/22090377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.127738.111 |
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