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BCL-2 family member BOK promotes apoptosis in response to endoplasmic reticulum stress
B-cell lymphoma 2 (BCL-2) ovarian killer (BOK) is a BCL-2 family protein with high homology to the multidomain proapoptotic proteins BAX and BAK, yet Bok(−/−) and even Bax(−/−)Bok(−/−) and Bak(−/−)Bok(−/−) mice were reported to have no overt phenotype or apoptotic defects in response to a host of cl...
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| Udgivet i: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4466744/ https://ncbi.nlm.nih.gov/pubmed/26015568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1421063112 |
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