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Intracellular localization of the BCL-2 family member BOK and functional implications

The pro-apoptotic BCL-2 family member BOK is widely expressed and resembles the multi-BH domain proteins BAX and BAK based on its amino acid sequence. The genomic region encoding BOK was reported to be frequently deleted in human cancer and it has therefore been hypothesized that BOK functions as a...

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Bibliografiske detaljer
Main Authors: Echeverry, N, Bachmann, D, Ke, F, Strasser, A, Simon, H U, Kaufmann, T
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3647236/
https://ncbi.nlm.nih.gov/pubmed/23429263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.10
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