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Intracellular localization of the BCL-2 family member BOK and functional implications

The pro-apoptotic BCL-2 family member BOK is widely expressed and resembles the multi-BH domain proteins BAX and BAK based on its amino acid sequence. The genomic region encoding BOK was reported to be frequently deleted in human cancer and it has therefore been hypothesized that BOK functions as a...

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Библиографические подробности
Главные авторы: Echeverry, N, Bachmann, D, Ke, F, Strasser, A, Simon, H U, Kaufmann, T
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3647236/
https://ncbi.nlm.nih.gov/pubmed/23429263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.10
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