BCL-2 family member BOK is widely expressed but its loss has only minimal impact in mice

BOK/MTD was discovered as a protein that binds to the anti-apoptotic Bcl-2 family member MCL-1 and shares extensive amino-acid sequence similarity to BAX and BAK, which are essential for the effector phase of apoptosis. Therefore, and on the basis of its reported expression pattern, BOK is thought t...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Ke, F, Voss, A, Kerr, J B, O'Reilly, L A, Tai, L, Echeverry, N, Bouillet, P, Strasser, A, Kaufmann, T
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2012
Sujets:
Original Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3354060/
https://ncbi.nlm.nih.gov/pubmed/22281706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.210
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