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BCL-2 family member BOK is widely expressed but its loss has only minimal impact in mice
BOK/MTD was discovered as a protein that binds to the anti-apoptotic Bcl-2 family member MCL-1 and shares extensive amino-acid sequence similarity to BAX and BAK, which are essential for the effector phase of apoptosis. Therefore, and on the basis of its reported expression pattern, BOK is thought t...
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| Asıl Yazarlar: | , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group
2012
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3354060/ https://ncbi.nlm.nih.gov/pubmed/22281706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.210 |
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