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BCL-2 family member BOK is widely expressed but its loss has only minimal impact in mice

BOK/MTD was discovered as a protein that binds to the anti-apoptotic Bcl-2 family member MCL-1 and shares extensive amino-acid sequence similarity to BAX and BAK, which are essential for the effector phase of apoptosis. Therefore, and on the basis of its reported expression pattern, BOK is thought t...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Ke, F, Voss, A, Kerr, J B, O'Reilly, L A, Tai, L, Echeverry, N, Bouillet, P, Strasser, A, Kaufmann, T
التنسيق: Artigo
اللغة:Inglês
منشور في: Nature Publishing Group 2012
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3354060/
https://ncbi.nlm.nih.gov/pubmed/22281706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.210
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