Circadian control of innate immunity in macrophages by miR-155 targeting Bmal1

The response to an innate immune challenge is conditioned by the time of day, but the molecular basis for this remains unclear. In myeloid cells, there is a temporal regulation to induction by lipopolysaccharide (LPS) of the proinflammatory microRNA miR-155 that correlates inversely with levels of B...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Curtis, Anne M., Fagundes, Caio T., Yang, Guangrui, Palsson-McDermott, Eva M., Wochal, Paulina, McGettrick, Anne F., Foley, Niamh H., Early, James O., Chen, Lihong, Zhang, Hanrui, Xue, Chenyi, Geiger, Sarah S., Hokamp, Karsten, Reilly, Muredach P., Coogan, Andrew N., Vigorito, Elena, FitzGerald, Garret A., O’Neill, Luke A. J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466714/
https://ncbi.nlm.nih.gov/pubmed/25995365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1501327112
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